Redefining the Management of Fuchs Dystrophy
Since its introduction in the United States in the mid-2010s, Descemet stripping only (DSO) has revolutionized the surgical management of Fuchs dystrophy. Although similar procedures were originally explored in the 1950s and for some time after, these met with little success.
The current technique—pioneered in the United States by Kathryn A. Colby, MD, PhD, the Elisabeth J. Cohen, MD, Professor of Ophthalmology and chair of the Department of Ophthalmology at NYU Grossman School of Medicine—involves removal of the diseased endothelium and mound-shaped aggregates, known as guttae, without the need for a donor graft.